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LRR1 Antibody, HRP conjugated

Datasheet
Code CSB-PA836247LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LRR1 Polyclonal antibody
Uniprot No.
Q96L50
Target Names
LRR1
Alternative Names
4 1BB mediated signaling molecule antibody; 4 1BBlrr antibody; 4-1BB-mediated-signaling molecule antibody; 4-1BBlrr antibody; Cyclophilin like 5 antibody; Leucine-rich repeat protein 1 antibody; LLR1_HUMAN antibody; LRR 1 antibody; LRR repeat protein 1 antibody; LRR-1 antibody; LRR-repeat protein 1 antibody; LRR1 antibody; MGC20689 antibody; peptidylprolyl isomerase (cyclophilin) like 5 antibody; Peptidylprolyl isomerase like 5 antibody; Peptidylprolyl isomerase-like 5 antibody; PPIL5 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Leucine-rich repeat protein 1 protein (18-159AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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LRR1 Antibodies

LRR1 Proteins

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Target Background

Function
May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Gene References into Functions
  1. Results identify the CRL2(LRR-1) ubiquitin ligase as a conserved regulator of Cip/Kip CKIs that promotes the degradation of C. elegans CKI-1 and human p21. PMID: 21074724
Tissue Specificity
Ubiquitous. Maximal expression was seen in the heart and skeletal muscle and minimal expression seen in the kidney.
Database Links

HGNC: 19742

OMIM: 609193

KEGG: hsa:122769

STRING: 9606.ENSP00000298288

UniGene: Hs.451090

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